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DNA content in neurons of Auerbach's plexus under experimental conditions in adult rats
Author(s) -
Robecchi M. G. Giacobini,
Poncino A.,
Geuna S.,
Giacometti S.,
Filogamo G.
Publication year - 1988
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(88)90034-2
Subject(s) - myenteric plexus , thymidine , dna synthesis , mitosis , dna , plexus , biology , ploidy , nerve cells , anatomy , microbiology and biotechnology , pathology , chemistry , biochemistry , immunohistochemistry , immunology , medicine , gene
Some nerve cells of the Auerbach's myenteric plexus of the intestine of the adult rat, which hypertrophied following a surgically induced stenosis, began DNA synthesis unrelated to mitotic division. The cytophotometric analysis confirmed and quantified the amount of synthesis revealed by autoradiography with tritiated thymidine uptake. Numerous nerve cells show a DNA content exceeding the diploid level. Only a few of these show twice the diploid content. The significance of the DNA synthesis is discussed.