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The prolactin cycle of the pseudopregnant female rat and the low‐o eeg activity in the ca, area of the hippocampus
Author(s) -
Anogianakis G.,
Apostolakis M.,
GuibaTziampiri O.,
KaikisAstaras A.,
Matziari C.
Publication year - 1985
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(85)90210-2
Subject(s) - physiology , medicine , human physiology
I . The extensor digitorum longus (edl) muscle of adult rats was removed, cut into pieces (minced) and replaced into i ts own bed. In another group of experiments the soleus muscle was also previously removed, and replaced the edl "mince". The reverse transplantat ion was also made with soleus muscle cut into small pieces and put in place of edl, 2. At intervals varying from 2-9 weeks the cont ract i le properties of the regenerated muscles were recorded and taken as an indicat ion of the i r recovery. The regenerated muscles never recovered more than hal f of the i r tension, even though the regeneration of the muscle t issue in the place of edl developed better than in the place of soleus, no matter whether the muscle tissue fragments came from edl or soleus muscle. 3. A combined cho] inesterase-si lver stain revealed that the pattern of innervation in the regenerated muscles was unusual in that many muscle f ibres had more than one end plate and many end plates more than one axon terminal. 4. These results show that in adult animals muscle redevelopment can occur only to a l imi ted extent, Moreover, on reinnervation of regenerated muscle f ibres the axons are unable to assume the i r or ig inal pattern of innervat ion.