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The effects of apomorphine and isoproterenol on the ‘transport response’ in the white rat
Author(s) -
Wilson Christopher
Publication year - 1985
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(85)90032-2
Subject(s) - apomorphine , agonist , dopaminergic , catecholaminergic , endocrinology , medicine , dopamine agonist , bromocriptine , chemistry , isoprenaline , pharmacology , dopamine , hormone , receptor , stimulation , prolactin
In a series of four experiments, the ability of specific catecholaminergic agonists to intensify the ‘transport response’ was investigated in 19‐, 32‐, 36‐ and 40‐day‐old rats. The dopaminergic agonist, apomorphine, was able to intensify the response in a dose‐dependent fashion. The beta‐noradrenergic agonist, isoproterenol, was unable to alter the intensity of the response. These results indicate a central dopaminergic involvement in the transport response.