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Novel explanation of proliferation of prolactin cells
Author(s) -
Hagino N.,
Inoue K.
Publication year - 1983
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(83)90331-3
Subject(s) - health science , citation , library science , curl (programming language) , medicine , computer science , world wide web , medical education
Great emphasis is being placed on the identif ication of neurotransmitter systems involved in the symptomatic manifestations of endocrinological disorders. Compellin~ evidence suggests that hypothalamic donaminergic neurons, whose cell bodies lie in the tuberoinfundibulum, are selectively involved in the disorders of prolactin secretion. Our study provides evidence that functional linkage of the hypothalamic dopaminergic neurons with prolactin cells initiated during fetal develonment; dopamine seems to be involved in the regulation of proliferation of prolactin cells. Therefore, altered profiles of the dopaminergic system during pregnancy influence the proliferation of prolactin cells in offspring.