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Modification of neuronal surface during embryonic development: Interaction with peanut lectin
Author(s) -
Gremo F.,
Manconi P.E.,
Porru S.,
Ennas M.G.,
Velluzzi De Muro M.L.
Publication year - 1983
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(83)90327-1
Subject(s) - human anatomy , anatomy , medicine , library science , computer science
Longitudinal patterns are well established in the cerebellum of various mammals (Voogd and Bigar~, 1980). Each longitudinal unit is connected with a specific cerebellar and/or vestibular nucleus. Histochemistry of these longitudinal patterns has the advantage of demonstrating whole patterns, which is in contrast to experimental approach (see Marani, 1981), but the disadvantage of not showing the cortico-nuclear connections, except for monoamine oxidase in the chicken (Marani, 1981). Criteria for cerebellar pattern formation are difficult to gain. However, acetylcholinesterase and the monoclonal human granulocyte antibody B 4 3 constitute means to follow the longitudinal organization of the rabbzt cerebellum durlng zts development. Both the acetylcholinesterase and the B4, 3 monoclonal pattern starts to be present around day 19 after conception till two weeks after birth. Within this presentation the AChE pattern will be demonstrated, while the antigen, the pattern and the ultrastructural localization will be shown for the monoclonal B4, 3 antibody.