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Cell lineage in the mannalian central nervous system
Author(s) -
Mullen R.J.
Publication year - 1983
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(83)90243-5
Subject(s) - salt lake , citation , library science , computer science , biology , paleontology , structural basin
neuroblasts that undergo similar division patterns. To a great extent the fates of cells in the nervous system are cell autonomous, although the fates of certain neuroblasts are determined by interactions with other cells. Programmed cell death is common during neurogenesis: 105 of the 463 neural cells generated die. To explore how genes control neuronal cell lineages anti cell fates, we have isolated and characterized neuronal developmental mutants. Some mutants are blocked in particular cell divisions, others undergo supernumerary cell divisions and still