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The arachnoid granulations of the newborn human: An ultrastructural study
Author(s) -
Gomez Daniel G.,
Ehrmann Jorge E.,
Potts D. Gordon,
Pavese Albert M.,
Gilanian Angela
Publication year - 1983
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/0736-5748(83)90040-0
Subject(s) - cerebrospinal fluid , ultrastructure , superior sagittal sinus , anatomy , subarachnoid space , pathology , medicine , surgery , thrombosis
Portions of the superior sagittal sinus and lacunae laterales containing arachnoid villi and granulations from 8 full‐term newborn babies were studied by transmission electron microscopy. Arachnoid proliferations from 3 subjects were distended and fixed in vitro by applying a differential pressure of 8 cm H 2 O to the subarachnoid aspect of the tissues. The remaining cases were fixed in a collapsed state. Distended arachnoid proliferations showed morphologic characteristics associated with similar functional structures in experimental animals: shortened and enlarged interendothelial spaces; micropinocytotic activity and a system of endothelial‐lined tubules. All this is taken as evidence that arachnoid proliferations in newborn babies could already be engaged in cerebrospinal fluid absorption.