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Clinical applications of flow cytometry in hematology and immunology
Author(s) -
Drouet Mireille,
Lees Olivier
Publication year - 1993
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/0248-4900(93)90117-w
Subject(s) - flow cytometry , hematology , biology , immunology , monoclonal antibody , hematology analyzer , antigen , clinical immunology , medical physics , computational biology , antibody , medicine , allergy
Summary— Rapid developments in computer technology combined with new fluorescent dyes and monoclonal antibody production have led to the development of a powerful tool: flow cytometry. The techniques of flow cytometry can be applied in a wide clinical field, from routine tasks to research in immunology and hematology. The availability of automated instruments and standardized sample preparation methods have led to its daily clinical use, helping diagnosis, prognosis or monitoring therapy. Further advances will be made with the introduction of multi‐parametric analysis ie quantification of antigen expression of cell surface antigens.