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Analysis and sorting of chromosomes by flow cytometry: New trends
Author(s) -
Métézeau Philippe,
Schmitz Annette,
Frelat Gerard
Publication year - 1993
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/0248-4900(93)90112-r
Subject(s) - biology , sorting , karyotype , flow cytometry , chromosome , microdissection , computational biology , genetics , evolutionary biology , gene , computer science , algorithm
Summary— Flow cytogenetic is widely used since 1975, and essentially contributes to caryotype analysis and chromosome sorting. The principles of experimentation and its possibilities and limitations are now well known. Recently several new technologies have appeared. What attitude should the cytometrist adopt regarding PCR, microdissection of chromosomes, in situ hybridization, slit‐scan flow cytometry or image analysis?