Premium
Nucleotide sequence of circular DNA molecules homologous to the 240 bp tandem repeats of the intergenic spacer of Drosophila melanogaster ribosomal DNA
Author(s) -
Degroote Fabienne,
Renault Sylvaine,
Picard Georges
Publication year - 1990
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/0248-4900(90)90330-6
Subject(s) - biology , tandem repeat , genetics , intergenic region , homologous chromosome , dna , homologous recombination , nucleic acid sequence , drosophila melanogaster , ribosomal dna , spacer dna , direct repeat , microbiology and biotechnology , gene , genome , base sequence , phylogenetics
Summary— We have determined the nucleotide sequence of ten 240 bp repeated sequences of the DNA intergenic spacer present in circular DNA molecules purified from D melanogaster embryos. No significant difference was found with the sequence of the chromosomal units. This suggests that most of the circular molecules homologous to the 240 bp repeats are generated by homologous recombination between adjacent chromosomal units.