Premium
Activation of a Plasmodium falciparum protease correlated with merozoite maturation and erythrocyte invasion
Author(s) -
BraunBreton Catherine,
Silva Luis Pereira
Publication year - 1988
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1016/0248-4900(88)90081-0
Subject(s) - protease , plasmodium falciparum , biology , malaria , microbiology and biotechnology , biochemistry , enzyme , immunology
Protease‐dependent processes of the P. falciparum schizogonic cycle are briefly described. The P. falciparum p76 protease is the first example of a biochemically regulated protease, the activation of which is related to merozoite maturation and/or erythrocyte invasion. The main known properties of the p76 protease are reviewed and some original results concerning its biosynthesis and biological properties are described.