Open AccessImproved synthesis of 5β-cholestane-3α,7α,12α, 26(27)-tetrol isomers from cholic acid
Author(s) -
R. Somanathan,
Skaidrite K. Krisans
Publication year - 1984
Publication title -
steroids
Language(s) - English
Resource type - Journals
eISSN - 1878-5867
pISSN - 0039-128X
DOI - 10.1016/0039-128x(84)90027-8
Subject(s) - cholic acid , cholestane , wittig reaction , chemistry , alpha (finance) , beta (programming language) , stereochemistry , bile acid , biochemistry , medicine , construct validity , nursing , computer science , patient satisfaction , programming language
Synthesis of a mixture of the 25(R) and 25(S) isomers of 5 beta-cholestane-3 alpha,7 alpha,12 alpha, 26(27)-tetrol from cholic acid in four steps, including a Wittig reaction, is described.