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Limited invasiveness to assess retroperitoneal spread in stage I–II ovarian carcinoma
Author(s) -
Zanetta G.,
Chiari S.,
Barigozzi P.,
Rota S.,
Losa G.,
Mangioni C.
Publication year - 1995
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(95)02455-l
Subject(s) - medicine , palpation , stage (stratigraphy) , lymphadenectomy , ovarian carcinoma , retroperitoneal space , radiology , surgery , lymph node , ovarian cancer , cancer , paleontology , biology
Objective: To evaluate the incidence of retroperitoneal metastases, survival rate and site of recurrence in early ovarian tumors undergoing limited retroperitoneal surgery. Method: Three hundred seventy‐three consecutive patients underwent assessment of the retroperitoneum consisting of intraoperative palpation with or without biopsies. Results: Retroperitoneal metastases were detected in 10 stage‐I tumors (3.2%) and in 10 stage‐II tumors (16%). The risk was inversely related to tumor differentiation. Palpation revealed metastases in 10 cases. During follow‐up, none of the borderline tumors (1.9% of stage‐I grade‐1 node‐negative, 2.7% of grade‐2 and 7.0% of grade‐3 tumors) recurred in the retroperitoneum. In stage II, two recurrences were observed in grade‐2 tumors (11%) and one in grade 3 (4.5%). Conclusion: Limited retroperitoneal surgery enables satisfactory outcome in early ovarian cancers. Risk of retroperitoneal recurrence is minimal in grade 1 and non‐existent in borderline tumors. Less differentiated tumors have low risk but further investigation of the therapeutic role of lymphadenectomy is justified.