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Dysgerminoma of the ovary in a patient with triple‐X syndrome
Author(s) -
Kemp B.,
Hauptmann S.,
Schröder W.,
AmoTakyi B.,
Leeners B.,
Rath W.
Publication year - 1995
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(95)02395-s
Subject(s) - dysgerminoma , ovary , karyotype , trisomy , pathology , biology , gynecology , chromosome , medicine , endocrinology , genetics , gene
A 24‐year‐old patient with dysgerminoma of the right ovary and hypoplastic left ovary was screened for chromosomal aberration. Triple‐X syndrome was found in the oral epithelium and lymphocyte culture, while chromosomal in situ hybridization of the tumor itself showed a normal XX karyotype. Although trisomy X and dysgerminoma are coincidental findings in our case report, women with malignant germ cell tumors and abnormal genitalia should be checked for chromosomal aberrations to exclude anomalies carrying a Y chromosome.