Premium
Perinatal outcome in pregnancies complicated by pulmonary tuberculosis
Author(s) -
Ja.,
Vasishta K.,
Jindal S.K.,
Khunnu B.,
Ghosh K.
Publication year - 1994
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(94)90064-7
Subject(s) - medicine , pulmonary tuberculosis , tuberculosis , gestational age , obstetrics , pregnancy , pediatrics , birth weight , fetus , perinatal mortality , gestation , pathology , biology , genetics
OBJECTIVES: To assess the perinatal outcome of pregnancies complicated by active pulmonary tuberculosis. METHODS: The perinatal outcome of 79 gravidas with pulmonary tuberculosis was compared with that of 316 normal gravidas of similar age, parity and socioeconomic status. RESULTS: The mean birthweight of infants (2649 g) born to tuberculous mothers was 215 g less than that of control group (P < 0.001). Pulmonary tuberculosis was associated with an approximate 2‐fold increase in prematurity (22.8% vs. 11.1%, P < 0.01), small for gestational age (20.2% vs. 7.9%, P < 0.005) and low birth‐weight neonates (34.2% vs. 16.5%, P < 0.001), and 6‐fold increase in perinatal deaths (10.1% vs. 1.6%, P < 0.001). The adverse perinatal outcome was pronounced in cases with late diagnosis, incomplete and irregular treatment, and advanced pulmonary lesions. CONCLUSIONS: Maternal tuberculosis is a high‐risk perinatal condition. The study emphasizes the need for early diagnosis and treatment of tuberculosis, preferably before pregnancy, regular medical supervision and good perinatal care for tuberculous mothers.