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Morphologic hysteroscopic criteria suggestive of endometrial hyperplasia
Author(s) -
Uno L.H,
Sugimoto O,
Carvalho F.M,
Bagnoli V.R,
Fonseca A.M,
Pinotti J.A
Publication year - 1995
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(94)02303-g
Subject(s) - medicine , hysteroscopy , metrorrhagia , gynecology , hyperplasia , endometrium , endometrial hyperplasia , predictive value , prospective cohort study , predictive value of tests , positive predicative value , exact test , population , radiology , obstetrics , urology , pathology , research methodology , environmental health , family planning
Objectives: To evaluate the morphologic hysteroscopic criteria leading to a diagnosis of endometrial hyperplasia and compare their accuracy with that of histology. Methods: A total of 95 hysteroscopic examinations were evaluated. Of these, 37 had a histologic diagnosis of normal endometrium and the remaining 58 of simple or complex endometrial hyperplasia. We compared the morphologic hysteroscopic criteria for the two groups using Pearson's chi‐squared and Fisher's exact test. Results: Only the presence of endometrial glands presenting a cystic pattern at hysteroscopy gave statistically significant results (P < 0.05), with low sensitivity (15.79%), high specificity (97.29%) and a relative risk of 6.75. With a prevalence of endometrial hyperplasia of 22.97% in a population of women with metrorrhagia, the positive predictive value was 63.53% and the negative predictive value was 79.40%. Conclusion: Additional, prospective studies are needed to determine the real value of the diagnostic morphologic parameters under consideration.