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Magnesium and calcium concentration in the pregnant and non‐pregnant myometrium
Author(s) -
Cunze T.,
Rath W.,
Osmers R.,
Martin M.,
Warneke G.,
Kuhn W.
Publication year - 1995
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(94)02217-8
Subject(s) - myometrium , medicine , magnesium , uterus , calcium , preterm labor , obstetrics , cervix , pregnancy , endocrinology , gestation , chemistry , biology , organic chemistry , cancer , genetics
Objectives: To investigate the effect of labor on the magnesium and calcium concentrations in the human myometrium and to compare them with the concentrations in the non‐pregnant uterus. Method: Samples of the isthmic part of the uterus were taken from 42 patients not in labor, 31 patients in regular labor during a cesarean section, and 37 premenopausal patients on whom a hysterectomy was performed. Results: (i) The magnesium concentration dropped significantly during labor; (ii) the calcium concentration in the tissue showed no significant changes during labor; (iii) the magnesium and calcium concentrations were significantly higher during pregnancy; (iv) the distribution of electrolytes in the myometrium differed significantly in the corpus, isthmus and cervix uteri. Conclusions: The electrolyte concentration in the myometrium depends on the place of removal. A low magnesium concentration in the pregnant human myometrium could be a cause of premature labor.