Premium
Total cholesterol, high density lipoprotein cholesterol and steroid hormone changes in normal weight women during the menstrual cycle
Author(s) -
Nduka E.U.,
Agbedana E.O.
Publication year - 1993
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(93)90554-a
Subject(s) - menstrual cycle , cholesterol , endocrinology , medicine , testosterone (patch) , hormone , high density lipoprotein , steroid , lipoprotein , menstruation , physiology , biology
OBJECTIVE: To study total cholesterol, high density lipoprotein cholesterol and steroid changes in normal weight women during the menstrual cycle. METHOD: Multiple point blood samples obtained at different phases of the menstrual cycle in 14 student nurses, consuming normal Nigerian diets (rich in vegetable based proteins and fiber), were analyzed for HDL cholesterol, total cholesterol and for the steroids progesterone, estradiol and testosterone by RIA. RESULTS: A multivariate repeated measures analysis was carried out according to Pillais, Hotelings Willes and Roys tests and the three phases of menstrual cycle were found to be significantly different with the significance level at 0.030. CONCLUSION: The fluctuations in plasma lipids that occur at different phases of the menstrual cycle have important implications in evaluating the factors of coronary heart disease in women of reproductive age. Also, the results suggest that multiple point measurements may give a better estimate of plasma lipid changes in blood in women of reproductive age.