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Serum prolactin levels in postpill amenorrheic patients
Author(s) -
Karaman A.S.,
Uran B.,
Erler A.
Publication year - 1993
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(93)90326-r
Subject(s) - medicine , prolactin , endocrinology , physiology , hormone
OBJECTIVES: In this study, we evaluated the importance of the determination of serum prolactin levels in postpill amenorrheic patients. METHODS: Serum estradiol and prolactin levels were determined in 37 postpill amenorrheic patients. Bromocriptine was administered to the hyperprolactinemic group and clomiphene citrate to the normoprolactinemic group. RESULTS: Hyperprolactinemia was observed in 21 patients (56.7%) and serum estradiol levels <50 pg/ml were found in 19 of these patients. The mean prolactin level was 71.90 ± 23.05 ng/ml in the hyperprolactinemic group. While bromocriptine had a significant effect on the length of time for menstrual bleeding to return (P < 0.001), clomifene had no effect. CONCLUSIONS: No treatment is required for the postpill amenorrheic patients with normal estradiol and prolactin levels. If hyperprolactinemia is detected, bromocriptine may be used as a treatment to promote normal menstrual bleeding and ovulation.