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Possible prodromes of human papillomavirus uterine cervix infection
Author(s) -
ArmbrusterMoraes E.,
Ioshimoto L.M.,
Leao E.,
Zugaib M.
Publication year - 1993
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(93)90224-k
Subject(s) - medicine , viremia , dysuria , human papillomavirus , cervix , biopsy , pathological , hpv infection , pathology , gynecology , virology , virus , cervical cancer , cancer , urinary system
We present two case reports and mention four others with similar clinical, pathological and laboratory findings which suggest that viremia could possibly occur in some human papillomavirus (HPV) infections. Fever, general indisposition or arthralgia associated with micturition difficulties or dysuria appear to be the symptoms accompanying this viremia. After a period of time these symptoms disappear and the infection shows typical HPV uterine cervix symptoms. The diagnosis of HP V infection was confirmed by histological analysis and DNA hybridization of biopsy material from the cervical lesions. These clinical findings may introduce a new avenue for the investigation of viral physiopathology.