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Outcome of cryosurgery for cervical intraepithelial neoplasia in a developing country
Author(s) -
Olatunbosun O.A.,
Okonofua F.E.,
Ayangade S.O.
Publication year - 1992
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(92)91023-h
Subject(s) - medicine , cryosurgery , colposcopy , cervical intraepithelial neoplasia , cure rate , obstetrics , pregnancy , adverse effect , intraepithelial neoplasia , gynecology , surgery , cervical cancer , cancer , prostate , biology , genetics
Over a 2‐year period cryosurgery was used to treat 73 women who were diagnosed by colposcopy and histologic studies to have cervical intraepithelial neoplasia (CIN). Follow‐up was achieved for 70% at 5 years, a significant attendance rate in a developing country. The primary cure rate was 88.5% at 1 year and 90% at 5 years (excluding those lost to follow‐up) in all patients with different grades of CIN. The therapy was free of major complications and we found no adverse effect of cryosurgery on subsequent reproductive function in those desiring pregnancy. We conclude that cryosurgery has gained wide acceptance in our geographic area particularly because of its low cost, efficacy and preservation of fertility. For these reasons we would strongly recommend its use provided adequate attention is paid to meticulous pretreatment evaluation and long‐term follow‐up after therapy.