Premium
Maternal alpha‐2‐macroglobulin levels and fetal growth in Guatemala
Author(s) -
Neel N.R.,
Goldenberg R.L.,
Tamura T.,
Cliver S.P.,
Avent K.,
Hoffman H.J.
Publication year - 1992
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(92)90725-x
Subject(s) - medicine , alpha (finance) , gestational age , alpha 2 macroglobulin , socioeconomic status , population , demography , fetus , pregnancy , fetal growth , obstetrics , macroglobulin , environmental health , surgery , construct validity , genetics , sociology , biology , patient satisfaction
Maternal serum alpha‐2‐macroglobulin ( α 2 M) levels were measured at the time of delivery in 244 women in the central highlands of Guatemala. Significantly higher α 2 M levels were found in thin women and in poor women. In multiple regression analysis controlling for gestational age, race, sex, maternal triceps skinfold thickness and socioeconomic status, high α 2 M levels were significantly associated with decreased birthweight. These findings agree with those in a predominantly black population in the United States and extend the relationship between α 2 M and decreased birth‐weight to a developing country.