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A new nonsurgical technique for termination of intrauterine pregnancy associated with large multiple uterine leiomyomas
Author(s) -
Buckshee K.,
Dhond A.J.
Publication year - 1992
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(92)90334-f
Subject(s) - medicine , pregnancy , methotrexate , obstetrics , uterine leiomyoma , leiomyoma , gynecology , surgery , genetics , biology
Medical termination of a first trimester intrauterine pregnancy associated with large and multiple leiomyomas posed a unique problem because the sac was inaccessible per vaginum for surgical or vacuum evacuation. The use of prostaglandins was contraindicated due to a past history of bronchial asthma. But intraamniotic and intraplacental instillation of methotrexate, 25 mg at each site, under ultrasound guidance resulted in termination of pregnancy. No side effects or complications were observed after the procedure.