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A comparative study of oral glucose tolerance tests in Nigerian women on three types of steroidal contraceptives
Author(s) -
Oyelola O.O.,
Olusi S.O.,
Ayangade S.O.
Publication year - 1991
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(91)90719-l
Subject(s) - medicine , pill , endocrinology , mestranol , glucose tolerance test , physiology , research methodology , population , family planning , pharmacology , insulin , insulin resistance , environmental health
Oral glucose tolerance tests (OGTT) were performed on 146 Nigerian women volunteers using one of three types of steroidal contraceptives: high‐dose combined pills; low‐dose combined pills and injectable progesterone. Twenty‐six appropriately matched nonusers served as controls. The OGTT curves were analysed using the H‐index (HI). Women on injectable progesterone and high‐dose combined pills, respectively, had significantly higher (P < 0.05) mean HI than the controls. The low‐dose combined pills had the least effect on carbohydrate metabolism.