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The daytime glucose profile as a standardized model for metabolic management of diabetes mellitus in pregnancy
Author(s) -
Thurnau G.R.,
Payne G.G.
Publication year - 1991
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(91)90533-b
Subject(s) - medicine , endocrinology , diabetes mellitus , pregnancy , insulin , plasma glucose , genetics , biology
On the basis of normative data from non‐diabetic gravidae, the daytime glucose profile (DGP) is introduced as a model for insulin management of diabetes mellitus in pregnancy. The DGP employs four preprandial (target level = 70 mg/dl) and three 1‐h post‐prandial glucose determinations (target level = 140 mg/dl). Insulin changes are based on a simple equation applied to individual glucose value difference between the patient (P) and target (T) levels (P − T/20). With the aid of this model, the average (± SD) of the daytime mean plasma glucose (DMG) levels of 22 pregnant women requiring insulin treatment (183 ± 36 mg/dl) approached normalization (114 ± 15 mg/dl) after 2–7 profile determinations (median = 3.5).