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An analysis of the prolactin surge
Author(s) -
Adejuwon C.A.
Publication year - 1991
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(91)90294-f
Subject(s) - prolactin , radioimmunoassay , medicine , endocrinology , population , antiserum , hormone , antibody , immunology , environmental health
Daily sera from normally menstruating women analysed by radioimmunoassay (RIA) with prolactin kits from NIH showed midcycle prolactin elevations coinciding with LH surge. No such elevations were observed with Serono prolactin kit. Sera assayed both at NIH and Population Council laboratories confirmed the higher prolactin values measured by NIH kit. Evaluation studies showed no antisera contamination in both kits, but confirmed LH‐contamination of the NIH hPRL VLS 4 tracer. This may explain the reported wide prolactin variations.