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A comparison of single prostaglandin E 2 vaginal tablet with prostaglandin E 2 vaginal pessaries for induction of labor at term
Author(s) -
ElMardi A.A.,
ElQarmalawi M.A.,
Siddik M.,
ElHaroni A.,
Ammar A.,
Madkoor S.A.
Publication year - 1991
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(91)90289-h
Subject(s) - medicine , labor induction , induction of labor , prostaglandin , prostaglandin e2 , term (time) , vagina , prostaglandin e , gynecology , obstetrics , preterm labor , pregnancy , oxytocin , surgery , gestation , biology , genetics , physics , quantum mechanics
This study represents the first of its kind in Kuwait. Two preparations of prostaglandin E 2 (PGE 2 ) have been compared as agents for induction of labor. In a randomized controlled study of 200 women of low parity and unfavorable cervical induction features, induction of labor by means of a single vaginal tablets of PGE 2 was compared with locally prepared PGE 2 vaginal pessaries. The gradual increase of uterine contractions and the establishment of labor in a similar way to that observed during spontaneous labor was more apparent after PGE 2 tablets. Labor induction was successful in 80% of patients in PGE 2 tablet group compared with 59% in PGE 2 pessaries group. The incidence of cesarean section was equal in both groups (4%), but none was performed due to uterine hyperactivity. The data presented indicate that the PGE 2 vaginal tablet is safe and effective in induction of labor in healthy women at term.