Premium
Globulines anormalment precipitables (GAP) in Nigerian users of progestogen‐only pill
Author(s) -
Wright E.A.,
Temple V.J.,
Kapu M.M.,
Mwaigwe M.M.
Publication year - 1990
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(90)90715-w
Subject(s) - medicine , pill , progestogen , family planning , gynecology , mestranol , levonorgestrel , population , obstetrics , research methodology , physiology , endocrinology , estrogen , pharmacology , environmental health
The globulines anormalment precipitables (GAP), which have been reported to be raised in current and former oral contraceptive users, were measured in Nigerian subjects which included male volunteers. The results showed that GAP were presnt in males who had never used contraceptives and that the mean values were lowest in intrauterine contraceptive device (IUD) users and highest in females who had never used any contraceptives. However, curent contraceptive users had lower mean GAP values than either former users or never users. It was therefore concluded that GAP levels alone cannot be used to predict the development of thromboembolic complications in pill users, and that ethinyl estradiol cannot be the main physiological stimulus for GAP synthesis.