Premium
The stability and short‐term fluctuation in serum oxytocinase activity in pregnancy
Author(s) -
Edebiri A.A.,
Mack D.S.,
McDonald D.J.,
Philips J.
Publication year - 1989
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(89)90604-8
Subject(s) - medicine , gestation , pregnancy , term (time) , coefficient of variation , obstetrics , endocrinology , chromatography , chemistry , genetics , biology , physics , quantum mechanics
Maternal serum samples obtained from 123 normal pregnant women between 28 and 40 weeks gestation were analysed for oxytocinase (EC 3.4.11.3) activity using s‐benzyl‐1‐cysteine‐4‐nitroanilide as substrate. Oxytocinase activity was found to be stable at varying temperatures, with a mean co‐efficient of variation of 5.0%. The short‐term flucutuation of oxytocinase activity had a mean coefficient of variation of 3.6%. There is no suggestion of a “pulsatile” release of oxytocinae from its placental origin.