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Cervical prostaglandin injection: a novel method of administration for ripening the cervix and induction of labor
Author(s) -
Shaala S.,
Darwish E.,
Anwar M.,
Rocca M.,
Ismail A.A.A.
Publication year - 1989
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(89)90405-0
Subject(s) - medicine , cervix , labor induction , ripening , bishop score , gestation , induction of labor , prostaglandin , prostaglandin e2 , obstetrics , gynecology , oxytocin , pregnancy , anesthesia , cancer , chemistry , food science , biology , genetics
Twenty pregnant women with ⩾36 weeks gestation and Bishop score of ⩽4 were subjected to either intracervical injection of PGE 2 (0.25 mg) every 4 h to ripen the cervix and induce labor (study group n = 10) or injection of only the diluent (control group n = 10). PGE 2 cases showed significant increase in Bishop score and were successfully induced. The mean induction‐establishment and induction‐delivery intervals were 4.3 ± 0.1 min and 6.07 ± 1.7 h, respectively. The control group showed no response. PGE 2 cervical injection is a safe and effective method for cervical ripening and labor induction.