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Umbilical cord gamma‐glutamyl transpeptidase and placental dysfunction
Author(s) -
Bartnicki J.,
Sledziewski A.,
Jóźwik M.,
Urban J.
Publication year - 1989
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(89)90125-2
Subject(s) - medicine , umbilical cord , placental insufficiency , fetus , placenta , endocrinology , cord , cord blood , hypoxemia , human placental lactogen , apgar score , pregnancy , immunology , surgery , biology , genetics
Placental dysfunction has been suspected if human placental lactogen level and/or cystine‐aminopeptidase activity were lower than 10th centile. Significant rise in gamma‐glutamyl transpeptidase (GGTP) has been found in samples of arterial cord blood of newborns born to mothers with placental insufficiency. We observed the relationship between GGTP activity and decrease in cord pH and lower Apgar score of corresponding infants. We suggest that chronic hypoxemia as a consequence of placental dysfunction may result in damage of fetal liver cells.