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The influence of different amounts of clomiphene citrate on follicle‐stimulating hormone, luteinizing hormone and estradiol levels and on the number and maturation of follicles
Author(s) -
Chryssikopoulos A.,
Antoniou A.,
Kassanos D.,
Vazoura E.
Publication year - 1988
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(88)90273-1
Subject(s) - luteinizing hormone , follicle , follicle stimulating hormone , endocrinology , medicine , follicular phase , hormone , clomifene , ovulation , ovulation induction
Sixty‐eight anovulatory women were divided into three groups according to the administered doses of clomiphene citrate (CC) (A 250 mg, B 500 mg, C 750 mg). Daily follicle‐stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E 2 ) measurements were performed. Follicular maturation was monitored by ultrasound. In the high‐CC dose group, a statistically significant FSH rise was noted. As a result, earlier selection of the dominant follicle (DF), faster increase in the DF diameter and increased E 2 production was found.