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Effect of some recent analgesics on labor pain and maternal and fetal blood gases and pH
Author(s) -
Wahab S.A.,
Askalani A.H.,
Amar R.A.,
Ramadan M.E.,
Neweigy S.B.,
Saleh A.A.
Publication year - 1988
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(88)90199-3
Subject(s) - pentazocine , nalbuphine , butorphanol , medicine , respiratory acidosis , anesthesia , metabolic acidosis , acidosis , analgesic , fetus , opioid , pregnancy , receptor , genetics , biology
This study attempts to determine the analgesic properties of nalbuphine, pentazocine and butorphanol during labor and their potential effects on maternal and fetal blood gases and pH. Butorphanol analgesia was superior to either nalbuphine or pentazocine in relieving labor pain. The studied analgesics caused significant maternal respiratory acidosis and fetal metabolic acidosis. These acidotic changes were most marked with pentazocine, moderate with nalbuphine and minimal with butorphanol.