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Postpartum glycated hemoglobin A 1c and glucose tolerance test in mothers of large babies
Author(s) -
Saleh A.K.,
Moussa M.A.,
Hathout H.
Publication year - 1988
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(88)90190-7
Subject(s) - medicine , glycated hemoglobin , gestational diabetes , glucose tolerance test , obstetrics , hemoglobin , gestation , pregnancy , diabetes mellitus , endocrinology , type 2 diabetes , insulin resistance , biology , genetics
An attempt to study macrosomia and carbohydrate metabolism was made by determination of glycated hemoglobin A 1c and by the oral glucose tolerance test (OGTT) in early puerperium. We studied 76 women who gave birth to large babies ⩾4.5 kg, 74 women whose babies were 3–4 kg as controls, and 36 type II diabetics. The median of HbA 1c concentration in the diabetics (8.06%) was significantly higher than in the controls (6.49%), and the large babies' mothers (6.48%), P < 0.001. No significant difference was found between HbA 1c or glucose intolerance in mothers of large babies and mothers with average size babies. HbA 1c showed an association with glucose levels in the diabetics and controls, P < 0.001, but not in the large baby group. Mothers of large babies were as old and obese as the diabetics. We speculate that the relationship of postpartum GTT, HbA 1c and gestational diabetes is unwarranted.