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Assessment of the glucose tolerance test in unselected pregnancy using 75 g glucose load
Author(s) -
Li D.F.H.,
Wang Z.Q.,
Wong V.C.W.,
Ma H.K.
Publication year - 1988
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(88)90080-x
Subject(s) - medicine , gestational diabetes , glucose tolerance test , gestation , diabetes mellitus , impaired glucose tolerance , endocrinology , pregnancy , abnormality , obstetrics , type 2 diabetes , insulin resistance , genetics , psychiatry , biology
A 75 g oral glucose tolerance test (OGTT) was performed in 618 unselected pregnant Chinese women between 24 and 28 weeks gestation. The glucose response at fasting, 1, 2 and 3 h were studied. At 2 h the glucose level at 2‐standard deviation and 4‐standard deviation above the mean came very close to the criteria of abnormality suggested by the World Health Organization (WHO): 8.3 mmol/l vs. 8.0 mmol/l for impaired glucose tolerance and 10.8 mmol/l vs. 11.0 mmol/l for gestational diabetes mellitus. The area under the glucose response curve also correlates best with the glucose levels at 2 h during the OGTT (y = 2.1x + 4.6, r = 0.885). The 75‐g OGTT interpreted with the WHO criteria seems appropriate for pregnant Chinese women. The 75‐g test has the added advantages of reducing administration cost and discomfort of the patients.