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The correlation of serum estrogens and androgens with bone density in the late postmenopause
Author(s) -
Deutsch S.,
Benjamin F.,
Seltzer V.,
Tafreshi M.,
Kocheril G.,
Frank A.
Publication year - 1987
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(87)90238-4
Subject(s) - medicine , estrone , dehydroepiandrosterone sulfate , androstenedione , endocrinology , hormone , dehydroepiandrosterone , bone density , densitometry , estrogen , androgen , osteoporosis
A pilot group of 16 women in the late postmenopause were evaluated for bone density by computerized axial tomography (CT) scanning and for hormonal milieu. A highly statistically significant positive correlation between lumbar‐3 spongiosum density and both dehydroepiandrosterone‐sulfate (DHEA‐S), r = 0.67; P < 0.005 and androstenedione (A), r = 0.56; P < 0.03 was found. No such correlations were observed with estradiol (E 2 ), estrone (E 1 ) or an array of other hormones. The results of this preliminary report indicate a clear association of weak androgens with bone density in the late postmenopause.