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Factors associated with clinical reactions to rubella vaccination in women
Author(s) -
Nakazono N.,
Fujimoto S.,
Wakisaka A.,
Ishii K.,
Ichinoe K.,
Aizawa M.
Publication year - 1987
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(87)90237-2
Subject(s) - medicine , vaccination , rubella , rubella vaccine , immunology , obstetrics , pediatrics , gynecology , measles
Abstract Two types of rubella vaccine were given to 272 seronegative healthy Japanese adult women. Clinical and laboratory studies on clinical reaction after vaccination were carried out on HI antibody response, HLA types, basal body temperature (BBT), menstrual cycles and serum progesterone levels of vaccinees. Clinical reactions were not associated with HLA types of vaccinees, but arthropathy occured significantly more often in women vaccinated at the progestational stage than in women vaccinated at the estrogenic stage.