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Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: Case report
Author(s) -
Atad J.,
Lissak A.,
Rofe A.,
Abramovici H.
Publication year - 1987
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(87)90188-3
Subject(s) - ductus arteriosus , medicine , pregnancy , fetus , obstetrics , prostaglandin , twin pregnancy , cardiology , biology , genetics
Indomethacin was administered to suppress premature uterine contractions in a twin pregnancy from the 27th until the 32nd week of pregnancy. Patent ductus arteriosus was diagnosed after delivery in one twin and persisted patent for a period of 4 weeks. A hypothesis of the constrictive influence of prostaglandin synthetase inhibitors on the fetal ductus arteriosus during intrauterine and neonatal periods is suggested.