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Ripening of the cervix with prostaglandin E 2 ‐gel. A randomized study with a new ready‐to‐use compound of triacetin‐prostaglandin‐E 2 ‐gel
Author(s) -
Kristoffersen M.,
Sande H.A.,
Sande O.S.
Publication year - 1986
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(86)90087-1
Subject(s) - medicine , randomized controlled trial , triacetin , cervix , prostaglandin , ripening , significant difference , surgery , biochemistry , food science , chemistry , cancer
A randomized study with a group of patients treated with a new ready‐to‐use triacetin‐prostaglandin E 2 ‐gel compared to a non‐treated group was conducted. The gel‐treated group showed a distinct difference in cervical score after 12 h and ten patients were delivered during this period without further inductim attempt compared to none in the control group. There was a significantly lower need for oxytocinstimulation in the treated group (P < 0.0005), but there was no difference in the cesarean section rate or instrumental delivery rate. No side‐effects were seen. This new gel seems effective and safe.