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Cyclophosphamide and cisplatinum combination chemotherapy for the treatment of epithelial ovarian carcinoma
Author(s) -
Hahn Karla,
Magrina Javier F.,
Masterson Byron J.
Publication year - 1985
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(85)90077-3
Subject(s) - medicine , cyclophosphamide , oncology , chemotherapy , ovarian carcinoma , carcinoma , gynecology , ovarian cancer , cancer
A review of 18 patients with Stage III epithelial ovarian carcinoma treated by surgery and followed by cyclophosphamide and cisplatinum combination chemotherapy is presented. At the end of 12 months from the initiation of chemotherapy, 88.9% of the patients were alive and 77.8% remained free of tumor progression. At the end of 2 years 77.8% of the patients were alive and 44.4% of the patients were free of tumor progression. The combination of cyclophosphamide and cisplatinum has low toxicity, a simple pattern of administration, and has provided satisfactory results.