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Post‐operative chemotherapy for ovarian carcinoma: A prospective study with cyclophosphamide
Author(s) -
Akinkugbe A.,
Uguru V.E.,
Mordi V.P.N.
Publication year - 1985
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(85)90075-x
Subject(s) - medicine , laparotomy , debulking , cyclophosphamide , chemotherapy , ovarian carcinoma , ovary , surgery , carcinoma , nitrogen mustard , ovarian cancer , cancer
Seventy consecutive patients with carcinoma of the ovary were managed in our unit by laparotomy and extensive debulking procedures over a period of 8 years. Intensive post‐operative chemotherapy was given with intravenous cyclophosphamide. The mean follow‐up period was 2.6 years. Our results showed that 19 patients with early disease (stages I and II) showed complete remission but seven subsequently died of recurrent disease. The others with more advanced disease showed little response to treatment.