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Plasma volume in normal pregnant Nigerian primigravidae
Author(s) -
Abudu O.O.,
Sofola O.A.
Publication year - 1985
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(85)90059-1
Subject(s) - nigerians , medicine , plasma volume , gestation , pregnancy , obstetrics , evans blue , gynecology , physiology , endocrinology , political science , biology , law , genetics
Plasma volume was measured in 10 non‐pregnant, healthy nulliparous Nigerian and 30 normal primigravid Nigerians at various times of gestation by the Evans blue dye dilution technique. The mean plasma volume of 2098 ml for the non‐pregnant Nigerians was statistically different (P < 0.001) from values in non‐pregnant caucasian primigravidae of comparable status. A mean maximum plasma volume increase of 1387 ml above non‐pregnant value was found. Essentially, pregnancy imposed a much higher physiological load on Nigerian primigravidae compared to caucasian primigravidae. There was a significant negative correlation between plasma volume and packed cell volume (PCV) in pregnancy (r = −0.51, P < 0.001), which may be related to excessive hemodilution in the primigravid Nigerian. Differences found may be due to geographical and/or racial factors.