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Carcinoembryonic antigen in high risk pregnancies
Author(s) -
Lolis D.,
Baltoyiannis P.,
Messinis I.E.
Publication year - 1984
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(84)90097-3
Subject(s) - medicine , amniotic fluid , carcinoembryonic antigen , obstetrics , gestation , meconium , umbilical cord , pregnancy , fetus , diabetes mellitus , gynecology , endocrinology , immunology , cancer , genetics , biology
The significance of carcinoembryonic antigen (CEA) measurement was evaluated in 25 pregnant women with diabetes mellitus, 15 Rh negative sensitized and nine prolonged pregnancies. Another 114 women with normal pregnancy served as controls. Values in maternal and umbilical cord serum and in amniotic fluid did not change appreciably through 24–42 weeks' gestation. No significant difference in maternal serum, cord serum and amniotic fluid CEA values was found between diabetic, Rh negative sensitized and normal pregnancies at the corresponding weeks. Similar findings were obtained in prolonged pregnancies, except the values in amniotic fluid which were significantly higher than in normal pregnancies due to the presence of meconium. These results suggest that the measurement of CEA in high risk pregnancies is not useful in predicting fetal condition.