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Maternal serum bile acid levels and fetal distress in cholestasis of pregnancy
Author(s) -
Laatikainen Timo,
Tulenheimo Annika
Publication year - 1984
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(84)90019-5
Subject(s) - fetal distress , bile acid , cholestasis , cholestasis of pregnancy , cardiotocography , fetus , medicine , obstetrics , pregnancy , distress , glycocholic acid , cholic acid , biology , clinical psychology , genetics
Cardiotocography (CTG) and serum total bile acid level were used in the perinatal surveillance of 117 pregnancies with intrahepatic cholestasis. Signs of fetal distress occurred more commonly in cholestasis pregnancies with high maternal bile acid levels. Despite careful monitoring one intrauterine fetal loss occurred without any warning signs in CTG. In this case the serum bile acid level was only moderately elevated. CTG seems to be suitable for detection of fetal distress in cholestasis pregnancies. Those with high maternal bile acid level should be subjected to a more intensive follow‐up. Some fetal risk, however, seems to remain despite of the use of these methods.