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Human placental lactogen, pregnancy‐specific beta‐1‐glycoprotein and alpha‐fetoprotein in serum in threatened abortion
Author(s) -
Hertz Jens B.,
SchultzLarsen Peter
Publication year - 1983
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(83)90047-4
Subject(s) - medicine , human placental lactogen , alpha fetoprotein , threatened abortion , obstetrics , abortion , pregnancy , vaginal bleeding , gynecology , gestational age , placental lactogen , endocrinology , andrology , fetus , placenta , biology , genetics , hepatocellular carcinoma
The predictive value of HPL, SP 1 and AFP in serum were determined in 109 women admitted to hospital because of vaginal bleeding in the 6th to 19th gestational week. The prediction of abortion based on the initial analysis from the day of admission was found to be 91.7%, 75.9% and 81.8% for HPL, SP 1 and AFP, respectively. The corresponding values for prediction of successful outcome were 68.7%, 73.6% and 65.4%. The HPL and AFP determinations were, however, found to be valid only after the 9th and 12th gestational week, respectively. A highly significant positive correlation (r = 0.84, P < 0.001) was demonstrated between HPL and SP 1 suggesting that SP 1 measurements might replace HPL in the evaluation of the prognosis in threatened abortion.