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Effect of oestrogen replacement therapy on blood coagulation factors in postmenopausal women
Author(s) -
Varma T.R.
Publication year - 1983
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(83)90019-x
Subject(s) - medicine , dydrogesterone , norethisterone , levonorgestrel , norgestrel , desogestrel , adverse effect , estrogen , estradiol valerate , myocardial infarction , breakthrough bleeding , gynecology , population , family planning , environmental health , research methodology
Natural oestrogens “Premarin”, (Ayerst, conjugated equine oestrogens) “Harmogen”, (Abbott, piperazine oestrone sulphate) and “Progynova” (Schering, oestradiol valerate) alone and in combination with proestational agents such as “Primolut N”, (Schering, norethisterone) “Neogest”, (Schering, norgestrel), “Norgeston”, (Schering, levonorgestrel), “Duphaston” (Duphar, dydrogesterone) did not have adverse effects on clotting factors. One patient developed deep vein thrombosis following treatment using “Progynova” (oestradiol valerate) alone and a second patient suffered from mild myocardial infarction following the use of “Premarin” (conjugated equine oestrogens) alone.