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Human ovulation and plasma oxytocin
Author(s) -
Kumaresan Perianna,
Kumaresan Malathi,
Hossini Mahmood,
Arellano Carolina,
Vasicka Alois
Publication year - 1983
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(83)90010-3
Subject(s) - luteal phase , ovulation , follicular phase , oxytocin , menstrual cycle , endocrinology , medicine , radioimmunoassay , luteolysis , hormone
Plasma oxytocin (OT) concentrations were measured by radioimmunoassay (RIA) method without extracting plasma in 11 normal menstruating women. Mean plasma OT level began to increase steadily from the 7th day of the menstrual cycle and this level rose up to 20 ± 5 μU/ml (Mean ± S.E.) on the 10th day of the cycle. OT level declined to 13 ± 6 μU/ml on the day of LH peak and continuously declined for another 2 days ‐ then rose. The OT level was higher during the follicular phase than during the luteal phase. In 1 individual OT measured in 2 cycles a year apart showed the highest level of OT coincided with LH and FSH peak and abruptly declined. When there was the highest level of progesterone, the OT level was measurable 1 out of 11 cycles. From this study, we conclude that OT may have a role in human ovulation either synergistically or alone with other ovulatory mechanisms and ovarian estradiol and progesterone control the secretion of OT and also suggests that OT may play some role in the regulation of the luteolysis and the menstrual cycle in women.