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Midtrimester abortion with intravenous administration of 15 methyl prostaglandin F 2α
Author(s) -
Mapa M.K.,
Kochhar U.,
Raghavan K.S.,
Devi P.K.
Publication year - 1982
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(82)90023-6
Subject(s) - medicine , vomiting , nausea , diarrhea , anesthesia , abortion , pregnancy , gestation , gastroenterology , biology , genetics
In a trial of 71 women, 15(S) 15 methyl PGF 2α was administered intravenously at the dose level of 1 μg/min for termination of pregnancy of between 11 weeks and 20 weeks of gestation. Sixty‐one subjects (85.9%) aborted within 30 h of administration of the drug. The mean induction abortion interval was 15.65 h. The mean number of episodes of vomiting and diarrhea was 0.9 and 0.6, respectively. The effectiveness of the method is comparable to that of intramuscular method of administration, but the side effects are much less in comparison.