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Effects of long‐term treatment with bromocriptine on pituitary prolactinoma in a male
Author(s) -
Ayalon D.,
Eckstein N.,
Homonnai Z.T.,
Paz G.F.,
Eshel A.,
Reider I.
Publication year - 1982
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(82)90010-8
Subject(s) - bromocriptine , medicine , prolactinoma , potency , libido , prolactin , adenoma , pituitary neoplasm , pituitary adenoma , decreased libido , endocrinology , pituitary gland , urology , hormone , chemistry , biochemistry , in vitro
Poor surgical results are obtained when operating on large prolactinomas, especially when an extrasellar growth is demonstrated. Several groups have reported tumor regression following bromocriptine treatment. A case report is presented of a young hyperprolactinemic man with a large pituitary adenoma with suprasellar extension, normal visual fields, decreased libido, impotence, hypogonadism and azoospermia. This man was treated with high doses of bromocriptine for a period of 5 months. A significant improvement of potency libido and sperm concentration associated with radiological evidence of a marked reduction of tumor size was noted following suppressive treatment with this ergot alkaloid.