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Sequencing and functional analysis of the genome of Bacillus subtilis strain 168
Author(s) -
Harwood Colin R.,
Wipat Anil
Publication year - 1996
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(96)00524-8
Subject(s) - bacillus subtilis , strain (injury) , computational biology , biology , genome , whole genome sequencing , genetics , gene , bacteria , anatomy
The international programme to sequence the 4.2 Mb genome of Bacillus subtilis , a model Gram‐positive bacterium, is a joint project involving European, Japanese and US research groups. To date ca. 3.0 Mb of the genome has been sequenced, with the remaining 1.2 Mb expected to be completed in 1997. The amenability of B. subtilis to genetic manipulation, combined with the availability of extensive expertise on its biochemistry and physiology, makes this bacterium a valuable organism in which to investigate the properties of genes for which functions cannot be readily ascribed by standard methods.